The most common side effect associated with nevirapine is rash and it may also cause asymptomatic or severe clinical hepatitis. The objective of the study is to find out the correlation between the skin rash and the liver enzymes. A total of 100 mothers were included in this study in PMTCT center at Namakkal government Hospital Liver enzymes were performed for all the mothers and qualitative HIV-1 DNA PCR was performed for the infants. Skin rashes were seen in 7%, one (14.3%) had elevated AST and another one (14.3%) had elevated ALT. Of 93 no skin rash mothers, elevation of AST in 19, ALT in 30, ALP in 2 and GGT was seen in 1. 7 infants of these mothers were found to be HIV-1 infected. There was no significant correlation between skin rashes and liver enzyme abnormalities in this study.
Loading....